ANTIFUNGAL EFFECT OF TURMERIC EXTRACT (Curcuma domestica) IN LIQUID SOAP FORMULATION AGAINST THE GROWTH OF Malassezia furfur ATCC 14521

  • Eliya Mursyida Universitas Abdurrab
  • Anellia Putri Tanjung Universitas Abdurrab
Keywords: Turmeric extract, Malassezia furfur, well diffusion method, Pityriasis versicolor, liquid soap

Abstract

Turmeric (Curcuma domestica) has been identified as a potential natural antifungal agent due to its curcuminoids and essential oils. Malassezia furfur, a lipophilic fungus, is commonly found on human skin but can become pathogenic, causing Pityriasis versicolor. This study aimed to evaluate the antifungal activity of turmeric extract in a liquid soap formulation against Malassezia furfur. A post-test only with control group design was used, employing the well-diffusion method to assess antifungal efficacy. Turmeric extract was incorporated into liquid soap at concentrations of 10%, 15%, and 20%, with positive (commercial antifungal soap) and negative (soap base) controls. The inhibition zones were measured using a vernier caliper, and data were analyzed using One-Way ANOVA followed by post hoc Bonferroni testing. Results showed that all formulations met the Indonesian National Standards (SNI). The highest inhibition zone was observed at 20% concentration (17,46 mm), while the lowest was at 10% concentration (15,80 mm). ANOVA analysis confirmed significant differences between groups (p < 0,05). The study concludes that turmeric extract in liquid soap formulations demonstrates antifungal activity against Malassezia furfur and has potential as a natural alternative to synthetic antifungal agents.

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Published
2025-06-30
How to Cite
Mursyida, E., & Tanjung, A. (2025). ANTIFUNGAL EFFECT OF TURMERIC EXTRACT (Curcuma domestica) IN LIQUID SOAP FORMULATION AGAINST THE GROWTH OF Malassezia furfur ATCC 14521. MEDFARM: Jurnal Farmasi Dan Kesehatan, 14(1), 23-31. https://doi.org/10.48191/medfarm.v14i1.523